Tuesday, October 20, 2015

CBC : Complete Blood Count

Complete blood count (CBC) is a very common diagnostic test. It is also called as Haemogram, Full Blood Count (FBC), or Full Blood Exam (FBE) and is performed for various reasons.

Parameters used in CBC

  • Haemoglobin
  • Red blood cell (RBC) count
  • Platelets or thrombocyte count
  • Mean platelet volume (MPV)
  • differential counts of white blood cells (WBC)
  • RBC indices such as mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), reticulocyte count, Red blood cell Distribution Width (RDW), and haematocrit (HCT)


Hematocrit (HCT, packed cell volume, PCV) measures the amount of space (volume) red blood cells take up in the blood. The value is given as a percentage of red blood cells in a volume of blood. 
MCV shows the size of the red blood cells.

MCH value is the amount of hemoglobin in an average red blood cell.

MCHC measures the concentration of haemoglobin in an average red blood cell. 

Red cell distribution width (RDW) can also be measured which shows if the cells are all the same or different sizes or shapes. 

Reticulocyte count is the number of young RBCs.

Mean platelet volume (MPV) measures the average amount (volume) of platelets. Mean platelet volume is used along with platelet count to diagnose some diseases. If the platelet count is normal, the mean platelet volume can still be too high or too low.



The above table indicates normal value range for adult male and female. Normal value ranges differ according to age.  Very small deviation from normal values are considered to be normal.


Interpretation of CBC Reports


Now we will learn how to use the above parameters in order to determine abnormalities. Small changes are often seen in our body and so small deviations from the normal value range must be considered normal.

High RBC count (condition called Polycythemia) may be due to
  • Increased RBC production
  • Some kidney disorder that causes excessive secretion of hormone Erythropoietin (that stimulates RBC production)
  • Low oxygen levels in blood for prolonged periods, living in hilly or oxygen deficient areas (in this case, there is nothing to worry)

High Haematocrit values may also be because of dehydration (since the fluid content of blood goes down in this case) along with the ones responsible for high RBC count.

Low RBC count (condition called Erythrocytopenia) and low haematocrit values are indicatives of Anaemia. Malaria, Haemorrhage (excessive bleeding), Chronic Kidney Disease and other conditions in which abnormaly high number of RBCs die in a short time span or RBC production is significant reduced (ex. deficiency of vitamin B12, folic acid) leads to Anaemia.

Low WBC counts hint to a weak immune system which may be due to 
  • Certain autoimmune disorder
  • Infection of liver, spleen
  • Less production of WBC 's because of some abnormality in white bone marrow
  • HIV or some other pathogen that attacks WBC's

Slight increase or small increase in WBC count is called Leukocytosis. This is mainly caused in response to entry of infectious agents in our body. Other causes may include 
  • Abnormality in white bone marrow
  • Inflammatory diseases like Rheumatoid arthritis
  • Damage to tissues
  • Physical or emotional stress
Increase in Eosinophil count (called Eosinophilia) is seen in case of allergy. Large increase in WBC count is called Leukaemia.


Reference: Goldman L, Schafer AI, eds. Cecil Medicine . 24th ed. Philadelphia


21 comments:

  1. Great Informations indeed...

    Very useful for Screening of Anemic Patients with "HAEMOCHECK" : Haemoglobin Color Scales Kits.

    Thanks,
    Sameer K, NSM.

    ReplyDelete
    Replies
    1. Never give up in life they all say no cure to HSV 2 which is a big lie I have pass through many process also i never believe there is really cure to HERPES until I meet Dr.Ehiaguna the doctor that have been helping many people for many years, I come across this doctor online when I was searching for cure online I found out about this man, and to my greatest surprise this man have the herbal medicine which I have been looking for years I explain my problem to him through the email I found on someone who testify about him also, Dr.Ehiaguna write me a reply and explain how the process work so after ordering for the medicine I got it within 4 days and I took it according to the way Dr.Ehiaguna instructed, I was so happy after two week I took the medicine there was very big change in my health when I was done with the process I go for test, I found out I am negative that was the day I have the tears of joy you can also get in contact with my doctor through his email now drehiaguna@gmail.com or you can also WhatsApp him +2348073908953. And He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC

      Delete
    2. Am Dearest from Vegas, thanks to Dr oniha who cured me from fibroid and irregular / painful menstruation with his herbal medication, this problem make me not to have a child for five years, until Dr oniha administered his herbal medication on me, but today, I now have a child I can call my own, if you are having similar problem, you can also reach Dr oniha on his email: dronihaspell@yahoo.com or WhatsApp him on +2347089275769

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  2. Nice nd useful information

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  3. There are some natural remedies that can be used in the prevention and eliminate diabetes totally. However, the single most important aspect of a diabetes control plan is adopting a wholesome life style Inner Peace, Nutritious and Healthy Diet, and Regular Physical Exercise. A state of inner peace and self-contentment is essential to enjoying a good physical health and over all well-being. The inner peace and self contentment is a just a state of mind.People with diabetes diseases often use complementary and alternative medicine. I diagnosed diabetes in 2010. Was at work feeling unusually tired and sleepy. I borrowed a cyclometer from a co-worker and tested at 760. Went immediately to my doctor and he gave me prescription like: Insulin ,Sulfonamides,Thiazolidinediones but Could not get the cure rather to reduce the pain but brink back the pain again. i found a woman testimony name Comfort online how Dr Akhigbe cure her HIV  and I also contacted the doctor and after I took his medication as instructed, I am now completely free from diabetes by doctor Akhigbe herbal medicine.So diabetes patients reading this testimony to contact his email     drrealakhigbe@gmail.com   or his Number   +2348142454860   He also use his herbal herbs to diseases like:SPIDER BITE, SCHIZOPHRENIA, LUPUS,EXTERNAL INFECTION, COMMON COLD, JOINT PAIN, EPILEPSY,STROKE,TUBERCULOSIS ,STOMACH DISEASE. ECZEMA, PROGENITOR, EATING DISORDER, LOWER RESPIRATORY INFECTION,  DIABETICS,HERPES,HIV/AIDS, ;ALS,  CANCER , MENINGITIS,HEPATITIS A AND B,ASTHMA, HEART DISEASE, CHRONIC DISEASE. NAUSEA VOMITING OR DIARRHEA,KIDNEY DISEASE. HEARING LOSSDr Akhigbe is a good man and he heal any body that come to him. here is email    drrealakhigbe@gmail.com    and his Number +2349010754824

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  5. My HSV healing testi- mony my mouth is short of words,I am so happy because dr_anuge7 healed me from HSV a herbalist from west Africa, I have been suf- fering from it for the past 2 years, I have spent money on different medication but it the same, until some lady testify about this dr_anuge7  I decided to give a try ,that how I found my self healed, can't keep this I got to testify too, Chat him up on watssap +2348164866838 or Gmail dranuge@gmail.com

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    Good luck.

    ReplyDelete
  7. Great Dr. imoloa herbal medicine is the perfect cure for the HIV virus, I was diagnosed of HIV for 8 years, and every day I always looking for research to find the perfect way to get rid of this terrible disease because I always know that what we need because our health is on earth . So, on my internet search I saw several testimonies about how Dr. imoloa can cure HIV with powerful herbal medicines. I decided to contact this man, I contacted him for herbal medicines that I received via DHL courier service. And he guided me how. I asked him for a solution to take herbal medicine for two weeks. And then he instructed me to go check what I was doing. Look at me (HIV NEGATIVE). Thank God for Dr. Imoloa for using a powerful herbal remedy to cure me. he also has a cure for diseases such as Parkison's disease, vaginal cancer, epilepsy, anxiety disorders, autoimmune diseases, back pain, sprains, bipolar disorder, brain tumors, malignant, bruxism, bulimia, cervical disc disease, cardiovascular disease, cardiovascular disease, sprains, bipolar disorder, brain tumors, malignant, bruxism, bulimia, cervical disc disease, cardiovascular disease, cardiovascular disease, sprains, bipolar disorder, brain tumors, malignant, bruxism, bulimia, cervical disc disease, cardiovascular disease , chronic respiratory diseases, mental and behavioral disorders, Cystic Fibrosis, Hypertension, Diabetes, asthma, autoimmune mediated arthritis. Chronic kidney disease, arthritis, back pain, impotence, feta alcohol spectrum, Dysthymic Disorders, Eczema, skin cancer, tuberculosis, Chronic Fatigue Syndrome, constipation, inflammatory bowel disease, bone cancer, lung cancer, mouth sores, oral cancer, body pain, fever, hepatitis ABC, syphilis, diarrhea, Huntington's disease, back acne, chronic kidney failure, Addison's disease, Chronic Disease, Crohn's Disease, Cystic Fibrosis, Fibromyalgia, Inflammatory Bowel Disease, Fungal Nail Disease, Paralysis, Celia Disease , Lymphoma, Major Depression, Malignant Melanoma, Mania, Melorheostosis, Meniere's Disease, Mucopolysaccharidosis, Multiple Sclerosis, Muscle Dystrophy, Rheumatoid Arthritis, Alzheimer's Disease email- drimolaherbalmademedicine@gmail.com / or {whatssapp .....+2347081986098}

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  10. I have been suffering from Polycystic Ovary Syndrome (PCOS) since my 20 years of age. Ever since i got married i have not been able to get pregnant, so i was completely barren due to this genetic disorder. I was prescribed several Clomid Meds but couldn't see any improvement. I would basically go from one outbreak to the next. Finally, on my best friend's recommendation about Dr James herbal mix medicine who cures all kinds of diseases with his herbal medicine, I decided to try his  herbal remedy which is made in liquid form with natural roots and herbs from Dr James. Within a few weeks, I could see improvements in the symptoms.
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    ReplyDelete
  11. I got tested of hepatitis B early this year, I experienced dark urine and ribs pain so I went to the hospital for treatment and I was diagnosed of HEP B. The doctor gave me anti-retroviral drugs to slowdown the viral load which later worsens the ailment because the drugs weren’t effective and I was so scared because they say it has no cure, out of frustration I told my friend about it and luckily he told me he ones battled same problem in the past but he was saved by Dr. Iyabiye. He gave me his contact and reached him and I became well and tested negative after the treatment. Here is his contact if you have such case. contact: +234-815-857-7300, (iyabiyehealinghome@gmail.com)

    ReplyDelete
  12. Hej det är laa! För 9 månader sedan berättade min läkare att jag fick diagnosen HSV2. Jag var hjärtbruten, men samma månad hittade jag en Dr Ricksin. som hjälpte mig att bota viruset med naturlig örtbehandling permanent. tack till Dr. Ricksin för hans naturliga växtbaserade behandling som eliminerat detta virus i min kropp för alltid. hans kontaktinformation för alla obotliga virus via; drricksin@gmail.com eller whatsapp honom eller ring honom via hans telefonnummer +3197005034579

    ReplyDelete
  13. Never give up in life they all say no cure to HSV 2 which is a big lie I have pass through many process also i never believe there is really cure to HERPES until I meet Dr.Ehiaguna the doctor that have been helping many people for many years, I come across this doctor online when I was searching for cure online I found out about this man, and to my greatest surprise this man have the herbal medicine which I have been looking for years I explain my problem to him through the email I found on someone who testify about him also, Dr.Ehiaguna write me a reply and explain how the process work so after ordering for the medicine I got it within 4 days and I took it according to the way Dr.Ehiaguna instructed, I was so happy after two week I took the medicine there was very big change in my health when I was done with the process I go for test, I found out I am negative that was the day I have the tears of joy you can also get in contact with my doctor through his email now drehiaguna@gmail.com or you can also WhatsApp him +2348073908953. And He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC

    ReplyDelete
  14. I was diagnosed of herpes virus, I have tried all possible means to get cure but all my effort proved abortive, until a friend of mine introduced me to a herbal doctor called Dr Agaba, who prepare herbal medicine to cure all kind of diseases including herpes virus (Herpes), when i contacted this herbal doctor via email, he sent me herpes virus herbal medicine via courier service, when i received the herbal medicine he gave me step by step instructions on how to apply it, when i applied it as instructed i was totally cured from the virus within 3 weeks of usage. Contact this great herbal doctor today to get your cure. 
    Via Email: Dragabasolutionhome@gmail.com or WhatApp: +2349074536486    

    ReplyDelete
  15. I am so Happy to be writing this article in here, i am here to explore blogs forum about the wonderful and most safe cure for HERPES SIMPLEX VIRUS.I was positive to the Virus called HERPES and i lost hope completely because i was rejected even by my closet friends. i searched online to know and inquire about cure for HERPES and i saw testimony about DR Ebhota online on how he cured so many persons from Herpes Disease so i decided to contact the great herbalist because i know that nature has the power to heal everything. i contacted him to know how he can help me and he told me never to worry that he will help me with the natural herbs from God! after 2 days of contacting him, he told me that the cure has been ready and he sent it to me via FEDEX or DHL and it got to me after 4 days! i used the medicine as he instructed me (MORNING and EVENING) and i was cured! its really like a dream but i'm so happy! that's the reason i decided to also add more comment of Him so that more people can be saved just like me! and if you need his help,contact his Email: (drebhotasoltion@gmail.com) You can contact him on WhatsApp +2348089535482 He also have the herb to cure difference cure for any sickness (1) HERPES,
    (2) DIABETES,
    (3) HIV&AIDS,
    (4) URINARY TRACT INFECTION,
    (5) HEPATITIS B,
    (6) IMPOTENCE,
    (7) BARENESS/INFERTILITY
    (8) DIARRHEA
    (9) ASTHMA..

    ReplyDelete
  16. Happiness is all i see now big thanks to Dr. Ubarlo from West Africa (NIGERIA), I never thought that I will live on earth before the year runs out. I have been suffering from a deadly disease herpes Virus for the past 2 years now; I had spent a lot of money going from one place to another, hospitals have been my home every day. Constant checks have been my hobby not until this blessed day, I was searching through the Internet, I saw a testimony on how Dr. Ubarlo. from West Africa (NIGERIA) helped someone in curing his herpes Virus . quickly I copied his Whatsapp Contact: +2348119508814 just to give him a test I spoke to him, he asked me to do some certain things which I did,he told me that he is going to provide the herbal cure to me, which he did, then he asked me to go for medical checkup after some days after using the herbal medication, I was free from the deadly disease, he only asked me to post the testimony through the whole world, faithfully am doing it now, please brothers and sisters, he is great, I owe him in return. if you are having a similar problem just contact him by Email: at drubarlohome@gmail.com whatsapp him on +2348119508814 HIS HAVE THE CURE TO THIS FOLLOWING DEADLY DISEASE [1] Ischemic heart disease [2] Cerebrovascular disease [3] Lower respiratory infections [4] Chronic obstructive pulmonary disease [5] Diarrhea diseases [6] Trachea, bronchus, lung cancers [7] Tuberculosis [8] Diabetes mellifluous [9] Hypertension heart disease [10] HIV/AIDS

    ReplyDelete
  17. Dr. Riaria cured my herpes virus that have been in my body since two years, ever since then my life has been incomplete, I have used so many drugs that was prescribed to me by doctors, but it didn't cure my herpes virus, i was checking for solution on the internet then I miraculously came across Dr. Riaria the powerful herbalist that  can cure herpes infection, then I contacted him through his email, I explained everything to him and he prepared a herbal medicine and sent it to me through FedEx, which I took for 14 days with the instruction he gave me, and when I did a test in the hospital my result came out negative it was the happiest day of my life that am cure from HSV 2,  are you also suffering from same virus or another diseases you can simply contact him via email: drriaria@gmail.com  you can also call or WhatsApp him on: +2349134987375.  

    ReplyDelete
  18. I was depressed when the doctor told me that I have been diagnosed with HERPES and HIV disease… I thought about my Family, I know my Family will face a serious problem when I'm gone, I lost hope and I wept all day, but one day I was searching the internet and I found Dr.0sagie contact number. +2347030465649 I called him and he guided me. I asked him for solutions and he started the remedies for my health. Thank God, now everything is fine, I'm cured by Dr.obudu herbal medicine, I'm very thankful to Dr.obudu and very happy with my hubby and family. email him on (drosagiesolutiontemple@gmail.com OR DROSAGIESOULTIONTEMPLE@YAHOO.COM ) o or you can also reach him through WhatsApp number+2347030465649 He can also cure so many sickness

    ReplyDelete

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